To Evaluate the Effect of Central Corneal Thickness on Diurnal Variation of Intraocular Pressure
Raziye Dönmez GÜN1, Alev KOÇKAR2, Nadir KOÇKAR3
1M.D. Gebze Fatih State Hospital, Eye Clinic, Kocaeli/TURKEY 2M.D. Asistant Professor, Istanbul Bilim University Faculty of Medicine, Department of Ophthalmology, Istanbul/TURKEY 3M.D. Uskudar State Hospital, Eye Clinic, Istanbul/TURKEY
Purpose: To evaluate the effect of central corneal thickness (CCT) on diurnal variation of intraocular pressure (IOP).
Materials and Methods: This retrospective study involved an evaluation of eyes of 52 patients, a total of 104 eyes, who were followed-up and
measured their IOP by the same physician between May 2012 and September 2013 in the eye clinic of Hakkari State Hospital. Patients were
grouped by their CCT (>520 μm and ≤520 μm) and diurnal IOP variation (≥5 mmHg and <5 mmHg).
Results: Of the 58% of patients (n=30) were male, and 42% (n=22) of them were female. Intraocular pressure (IOP) of the subjects who had
CCT ≤520 μm were found significantly lower at all measurements (p<0.01). It was found that mean IOP of the subjects were lower in the
afternoon hours than in the morning (p<0.05). Subjects who had CCT >520 μm had significantly more ≥5 mmHg IOP fluctuation (p<0.05) .
Conclusion: IOP fluctuation may cause false results in patients with high CCT. Therefore, patients need to be evaluated carefully in terms of
other parameters which cause risk for glaucoma.
Central corneal thickness, diurnal variation of intraocular pressure