Prevalance and Prognosis of Elevated Intraocular Pressure in Presumed Herpetic Anterior Uveitis
Irmak KARACA1, Suzan Güven YILMAZ2, Halil ATEŞ3
1M.D. Asistant, Ege University Faculty of Medicine, Department of Ophthalmology, Izmir/TURKEY 2M.D., Ege University Faculty of Medicine, Department of Ophthalmology, Izmir/TURKEY 3M.D. Professor, Ege University Faculty of Medicine, Department of Ophthalmology, Izmir/TURKEY
Purpose: To determine the prevalence of elevated intraocular pressure (IOP) and to investigate the effect of clinical signs on its prognosis in
patients with presumed herpetic anterior uveitis.
Materials and Methods: The medical records of patients diagnosed as herpetic anterior uveitis were reviewed. Patients were divided into 3
groups, as having normal IOP during the course (Group 1), ocular hypertension (OHT) (Group 2) and secondary glaucoma (Group 3). Relationship
between clinical signs and outcomes were investigated.
Results: Sixty-six eyes of 66 patients (32 female, 34 male) were included in the study. The mean age was 49.2±18.9 (10-80) years, the mean
follow-up time was 20.7±23.2 (3-108) months. During follow-up elevated IOP was noted in 41 eyes (62.1%). Fourteen of them (34.1%) were
evaluated as having glaucomatous defect. IOP was regulated with medical treatment in 7 eyes (50%), however other 7 eyes required surgical
intervention. There was no difference in between groups, regarding anterior segment reaction severity, number of attacks and recurrence rates
(p=0.332, p=0.098, p=0.457; Mann Whitney U test). Presence of granulomatous KPs was more prevalent in Group 2 and corneal vascularization
was higher in Group 3, significantly (p=0.041, p:0.003; chi-square test).
Conclusion: Elevated IOP is considerably common (%62.1) in patients with herpetic anterior uveitis; however only quite a few of them
(17.1%) requires surgery. Presence of granulomatous KPs was related with increased prevalence of OHT. As an indicator of disease severity
and chronicity, corneal vascularization was related with increased glaucoma risk.