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¹M.D., Ministry of Health Ulucanlar Education and Research Hospital Eye Clinic Ankara/TURKEY
²M.D. Associate Profesoor, Ministry of Health Ulucanlar Education and Research Hospital Eye Clinic Ankara/TURKEY
³M.D. Profesoor, Ministry of Health Ulucanlar Education and Research Hospital Eye Clinic Ankara/TURKEY Purpose: To investigate the etiologies and clinical features of patients with intraocular pressure (IOP) rise secondary to uveitis.
Materials and Methods: The data of 1314 patients who were followed in the Uvea - Behçet section between 2005 and 2011 were retrospectively evaluated and the medical records of 121 patients who had taken anti-glaucomatous agents because of secondary uveitic glaucoma or IOP rise were retrieved.
Results: IOP rise or secondary glaucoma was detected in 121 (9.2%) patients with uveitis. Of these patients, 40 (33.1%) had Behçet's disease, 28 (23.1%) had herpetic uveitis, 18 (14.9%) had Fuchs' uveitis, 13 (10.7%) had idiopathic uveitis, 5 (4.2%) had HLA-B27 associated uveitis, 4 (3.3%) had pars planitis, 3 (2.5%) had ankylosing spondylitis, 2 (1.7%) had multifocal choroiditis, and 2 (2.5%) had Vogt Koyanagi Harada disease. Toxoplasmosis, toxocariasis, sarcoidosis, familial Mediterranean fever, Lyme disease, and serpiginous choroiditis were observed in 1 patient each (0.8%). Trabeculectomy with mitomycin C was performed in 12 (9.9%) patients and suprachoroidal seton implantation was performed in 5 (4.1%) patients. IOP could be controlled with surgical excision of sub-tenon triamcinolone acetonide deposits in a patient (0.8%) with intermediate uveitis who received a posterior sub-tenon injection of triamcinolone.
Conclusion: IOP rise secondary to uveitis was observed in 9.2% of our cases and 14.8% of patients needed a surgical procedure. Behçet's disease was found to be the most commonly associated reason for IOP rise or glaucoma secondary to uveitis and the need for surgical treatment of glaucoma was higher in patients with Behçet's disease. Keywords : Behçet’s disease, glaucoma, herpes, intraocular pressure, uveitis