2Prof. Dr., Mersin Üniversitesi Tıp Fakültesi, Göz Hastalıkları Anabilim Dalı, Mersin, Türkiye
3Asist. Dr., Mersin Üniversitesi Tıp Fakültesi, Biyokimya Anabilim Dalı, Mersin, Türkiye
4Prof. Dr., Mersin Üniversitesi Tıp Fakültesi, Biyokimya Anabilim Dalı, Mersin, Türkiye
5Yrd. Doç. Dr., Mersin Üniversitesi Tıp Fakültesi, Göz Hastalıkları Anabilim Dalı, Mersin, Türkiye Purpose: To evaluate the systemic high sensitivity C-reactive protein (hs-CRP) levels in pseudoexfoliation syndrome (PES).
Materials and Methods: Thirteen cases with PES, 9 cases with pseudoexfoliation glaucoma (PEG) and 24 control subjects were included to our prospective controlled study. All of the cases were between 40 and 80 year-old and none of them had histories of any systemic medicine, systemic hypertension, diabetes mellitus, cardiovascular disease, chronic liver or kidney disease, any type of malignancy, any type of infection and infl ammatory diseases.
Results: No statistically signifi cant difference was observed in terms of age, gender and body mass index between groups (p>0.05). The median value of the hs-CRP in the study group was 3.00 mg/dl (0.3-160.9 mg/dl), while it was 3.70 mg/dl (0.4-97.4 mg/dl) in the control group. There was no statistically signifi cant difference between the groups in terms of hs-CRP values (p>0.05).
Conclusion: There were no signifi cant changes in hs-CRP levels between the cases with PES compared with healthy subjects. Keywords : High sensitivity C-reactive protein, pseudoexfoliation syndrome, vascular endothelial dysfunction, atherosclerosis
