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Automated Perimetry
Carbonic Anhydrase Inhibitors
Intra Ocular Lens Power Calculation and Optic Biometry...
Visual Field Defects in Glaucoma
Visual Field Defect and Retinal Nerve Fiber Layer Defect in a Case of Optic Nerve Head Drusen...
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Visual Field Defect and Retinal Nerve Fiber Layer Defect in a Case of Optic Nerve Head Drusen...
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TJ-CEO 2020 , Vol 15 , Num 1
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Evaluation of Corneal Endothelium and Retinal Nerve Fiber Parameters in Patients with Unilateral Pseudoexfoliation
Mehmet COSKUN
Assistant Prof., Ophthalmology Department of Karabuk University, Karabuk, Turkey DOI : 10.37844/glauc.cat.2020.15.4 Purpose: Evaluation of corneal endothelium and retinal nerve fi ber values in patients with unilateral pseudoexfoliation (PEX).

Material and methods: The patients were retrospectively evaluated; 30 eyes of 30 patients with unilateral PEX were specifi ed as group 1, the contralateral 30 eyes of the same 30 patients without PEX were designated as group 2, and 30 right eyes of sex and age-matched healthy subjects were evaluated as a controls group (group 3). The study group consisted of 30 participants in total.

Central corneal thickness (CCT), endothelial cell density (CD), coeffi cient of variation (CV) and hexagonality (HEX) parameters were analyzed, which were measured using specular microscopy. Retinal nerve fi ber thickness of the superior (SRNFL), nasal (NRNFL), inferior (IRNFL) and temporal (TRNFL) quadrants and also ganglion cell inner plexiform layer thickness (GC-IPL) were measured using optical coherence tomography and analyzed.

Results: The mean age of study group was 64,66±7,04 years. In group 2, SRNFL, NRNFL and IRNFL were signifi cantly higher than in group 1; no other parameters showed any signifi cant difference. SRNFL, NRNFL, IRNFL and TRNFL values were signifi cantly higher in group 3 than in group 1; no other parameters were signifi cantly different. IRNFL and TRNFL values were signifi cantly lower in group 2 compared with group 3, no other signifi cant differences were found between these two groups.

Conclusions: In patients with PEX, there were no difference in corneal endothelial parameters when compared with the contra lateral eyes of same patients with no PEX and eyes of healthy controls, whereas thinning was observed in some quadrants in terms of RNFL thickness. Keywords : Pseudoexfoliation, Specular microscopy, Retinal nerve fiber

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