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Automated Perimetry
Carbonic Anhydrase Inhibitors
Intra Ocular Lens Power Calculation and Optic Biometry...
Visual Field Defects in Glaucoma
Visual Field Defect and Retinal Nerve Fiber Layer Defect in a Case of Optic Nerve Head Drusen...
Current Minimal Invasive Angle Procedures Without Implants for the Treatment of Glaucoma...
Intra Ocular Lens Power Calculation and Optic Biometry...
Automated Perimetry
Carbonic Anhydrase Inhibitors
Visual Field Defect and Retinal Nerve Fiber Layer Defect in a Case of Optic Nerve Head Drusen...
PureSee Kesintisiz Yüksek Kalitede Görüş
TJ-CEO 2021 , Vol 16 , Num 2
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The Relationship Between Optic Nerve Head and Peripapillary Vascular Densities and Visual Field Analysis in Open Angle Glaucoma
Ahmet Kaderli1, Sinem Karabulut2, Sema Tamer Kaderli2, Cansu Kaya3, Aylin Karalezli4
1Assistant Prof., Muğla Sıtkı Koçman University, Ophthalmology, Muğla, Turkey
2MD., Muğla Sıtkı Koçman University, Research and Training Hospital, Ophthalmology, Muğla, Turkey
3MD., Muğla Sıtkı Koçman University, Ophthalmology, Muğla, Turkey
4Prof., Muğla Sıtkı Koçman University, Ophthalmology, Muğla, Turkey
DOI : 10.37844/glauc.cat.2021.16.19 Purpose: To correlate optic nerve head and peripapillary micro-vascular changes as detected by optical coherence tomography angiography (OCT-A) with visual field (VF) deviation parameters and retinal nerve fi ber layer (RNFL) thickness in open angle glaucoma.

Materials and Methods: Forty-eight eyes of 48 patients with primary open angle glaucoma (POAG) and 46 eyes of 46 patients with pseudoexfoliation glaucoma (PEG) were included in the study. Total, intra-disc and peripapillary (all quadrants) vascular densities (VD) were evaluated with OCT-A. All patients underwent 24-2 standard automated perimetry and mean deviation (MD) -pattern standard deviation (PSD) values were obtained. Patients with optic nerve pathologies, intraocular pressure ?25mmHg and media opacities were excluded from the study.

Results: The VF MD values were negatively correlated with all OCT-A parameters in POAG and with all quadrants other than intra-disc and nasal-inferior quadrant in PEG. While there was a signifi cant negative correlation between PSD and total image, peripapillary, nasal-inferior, inferior-nasal, inferior-temporal, temporal-inferior, temporal-superior and superior-temporal quadrants in POAG, there was no signifi cant correlation in any parameters other than intra-disc in PEG. When RNFL and OCT-A values were considered, signifi cant positive correlation was detected in all peripapillary micro-vascular parameters other than intra-disc capillary density in both POAG and PEG groups and the temporal-superior quadrant in POAG group.

Conclusion: The signifi cant correlation between VF MD value and peripapillary and optic nerve head VD measurements detected by OCT-A value may indicate that OCT-A measurements in the most common glaucoma types may be a potential biomarker in terms of glaucomatous functional damage. Keywords : Optical Coherence Tomography Angiography; Peripapillary Vascular Densities; Visual Field

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