TJ-CEO
2008 , Vol 3 , Num 2
Clinical Features of a Pediatric Case of Topiramate Induced Acute Angle Closure Glaucoma
1Karadeniz Teknik Üniversitesi, Tıp Fakültesi, Göz Hast. A.D., Trabzon, Doç. Dr.2Karadeniz Teknik Üniversitesi, Tıp Fakültesi, Göz Hast. A.D., Trabzon, Yard. Doç. Dr.
3Karadeniz Teknik Üniversitesi, Tıp Fakültesi, Göz Hast. A.D., Trabzon, Uzm. Dr.
4Karadeniz Teknik Üniversitesi, Tıp Fakültesi, Göz Hast. A.D., Trabzon, Prof. Dr. Clinical findings of a 12-year-old girl admitted to our clinic with the complaints of decreased vision and redness in both eyes that had started a day before were evaluated. The patient had been on topiramate treatment during the previous week due to headaches. Corrected visual acuities at the time of admission were 0.1 on the right and 0.2 on the left. Refractive indices were -9.00D on the right and -8.00D on the left. The biomicroscopic examination showed conjunctival hyperemia in both eyes, narrowing of the anterior chamber, and closure of the iridocorneal angle. Intraocular pressure was 28 mmHg on the right and 27 mmHg on the left. In the ultrasonographic biomicroscopy examination (UBM), accompanying supraciliary choroideal effusion there was narrowing of the anterior chamber due to anterior displacement of the iris-lens diaphragm, closure of the iridocorneal angle, choroid detachment, and increased thickness of the ciliary body. The topiramate treatment was stopped. The patient was administered antiglaucomatous drugs, oral carbonic anhydrase inhibitors, and non-steroid anti-inflammatory treatment. On the third day of the treatment, there was improvement in all ocular symptoms and findings, and the treatment was stopped. Keywords : Angle-closure glaucoma, intraocular pressure, myopia, topiramate, treatment