TJ-CEO
2012 , Vol 7 , Num 2
Comparison of Central Corneal Thickness Values Measured with Different Instruments in Advanced Aged Patients
1M.D., Special Tekden Hospital, Eye Clinic, Kayseri/TURKEY2M.D., Kayseri Training and Researh Hospital Eye Clinic, Kayseri/TURKEY Purpose: To compare the central corneal thickness (CCT) measured with different instruments in advanced aged patients and to assess the congruity and the correlation between the devices.
Materials and Methods: 30 eyes of 30 patients (16 men, 14 women) with a mean age of 66±9 years (51-84) were included in the study. The CCT of the patients was measured with Scheimpflug camera, non-contact specular microscopy and ultrasound (US) pachymetry. The difference, congruity and correlation of CCT measurements were assessed statistically between the instruments.
Results: Mean CCT measurements were 540.9±26.9 μm (479-589) for Pentacam, 524.9±25.7 μm (465-589) for US, 509.4±26.7 μm (444-572) for specular microscopy. The 95% limits of congruity were 42.6 and -10.5 μm for Pentacam-US pachymetry, 58.2 ve 4.9 μm for Pentacam-specular microscopy and 31.3 ve -0.4 μm for US pachymetry-specular microscopy. The measurements taken with all instruments showed significant correlation (r=0.871 p<0.001 for Pentacam-specular microscopy, r=0.863 p<0.001 for Pentacam-US pachymetry and r=0.953 p<0.001 for US pachymetry-specular microscopy).
Conclusion: Pentacam and specular microscopy show good correlation and congruity with US pachymetry which is considered as golden-standard in measurements of corneal thickness and there is no significant difference between the measurements with these instruments and the measurements with US pachymetry. However, the CCT measurements taken with Pentacam are higher compared to those taken with specular microscopy. Therefore, these two devices should not be used interchangeably. Keywords : Corneal thickness, pentacam, ultrasound pachymetry, specular microscopy